Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.44 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132986 | 0.87 | BCAT2 (1.00) | BCAT2KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL29427545 | 0.87 | BCAT2 (1.00) | BCAT2KMT2AMEN1SMN1; SMN2NPC1 | |
| Alanine SCHEMBL28126833 | 0.86 | BCAT2 (0.55) | BCAT2KMT2AMEN1SMN1; SMN2CHRNB2 | |
| Urea SCHEMBL28572437 | 0.85 | BCAT2 (0.96) | BCAT2KMT2AMEN1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL5180095 | 0.85 | BCAT2 (0.96) | BCAT2KMT2AMEN1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL1785690 | 0.85 | BCAT2 (0.96) | BCAT2KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL28355265 | 0.85 | BCAT2 (0.96) | BCAT2KMT2AMEN1SMN1; SMN2NPC1 | |
| Ammonia Solution, Strong SCHEMBL28275782 | 0.85 | BCAT2 (0.96) | BCAT2KMT2AMEN1SMN1; SMN2NPC1 | |
| Alanine SCHEMBL28776159 | 0.85 | KMT2A (0.50) | BCAT2KMT2AMEN1SMN1; SMN2FGFR1 | |
| Methane SCHEMBL27520060 | 0.85 | BCAT2 (0.96) | BCAT2KMT2AMEN1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663174-A | ANTIINFLAMMATORY AGENTS, INHIBITOR OF KINASES, ANTIARTHRITIC AGENTS | PHARNO-WEDROPHARM GMBH (DE) | 1997-09-02 | — | — | US | disclosed |
| EP-0602028-B1 | AROMATIC SULFONAMIDE DERIVATIVES, THEIR USE AS ENZYME INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARNO WEDROPHARM GMBH (DE) | 1996-01-17 | — | — | EP | disclosed |
| EP-0602028-A1 | AROMATIC SULFONAMIDE DERIVATIVES, THEIR USE AS ENZYME INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | PHARNO WEDROPHARM GMBH (DE) | 1994-06-22 | — | — | EP | disclosed |
| WO-1993005014-A1 | AROMATIC SULFONAMIDE DERIVATIVES, THEIR USE AS ENZYME INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARNO-WEDROPHARM GMBH (DE) | 1993-03-18 | — | — | WO | disclosed |