Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917765 | 0.95 | LTA4H (0.56) | LTA4HNPC1RAB9ADRD2MEN1 | |
| SCHEMBL8915859 | 0.91 | LTA4H (0.54) | LTA4HMEN1KMT2AKDM4EESR1 | |
| SCHEMBL8916661 | 0.86 | LTA4H (0.54) | LTA4HMEN1KMT2AKDM4EESR1 | |
| SCHEMBL8917616 | 0.81 | LTA4H (0.60) | LTA4HNPC1RAB9ADRD2MEN1 | |
| SCHEMBL8845640 | 0.81 | LTA4H (0.60) | LTA4HNPC1RAB9ADRD2MEN1 | |
| SCHEMBL12406933 | 0.77 | LTA4H (0.77) | LTA4HNPC1RAB9ADRD2MEN1 | |
| SCHEMBL8918082 | 0.77 | LTA4H (0.55) | LTA4HNPC1RAB9ADRD2MEN1 | |
| SCHEMBL8916213 | 0.74 | CYP2D6 (0.53) | LTA4HMEN1KMT2AKDM4EESR1 | |
| SCHEMBL8915518 | 0.72 | LTA4H (0.55) | LTA4HNPC1RAB9ADRD2MEN1 | |
| SCHEMBL8915699 | 0.72 | LTA4H (0.58) | LTA4HMEN1KMT2AESR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658951-A | ANTIESTROGENS, ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-08-19 | — | — | US | disclosed |