Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 5/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915518 | 0.94 | LTA4H (0.55) | LTA4HKEAP1NFE2L2LSSHRH3 | |
| SCHEMBL8916213 | 0.88 | CYP2D6 (0.53) | LTA4HHRH3HTR6ESR1CYP2D6 | |
| SCHEMBL9839159 | 0.86 | LTA4H (0.52) | LTA4HKEAP1NFE2L2LSSHRH3 | |
| SCHEMBL9839168 | 0.83 | LTA4H (0.49) | LTA4HLSSHRH3HTR6LMNA | |
| SCHEMBL8845495 | 0.80 | LTA4H (0.58) | LTA4HKEAP1NFE2L2LSSHRH3 | |
| SCHEMBL8915871 | 0.80 | LTA4H (0.58) | LTA4HKEAP1NFE2L2LSSHRH3 | |
| Hydrochloric Acid SCHEMBL10574784 | 0.79 | LTA4H (0.56) | LTA4HKEAP1NFE2L2LSSHRH3 | |
| SCHEMBL8916605 | 0.77 | LTA4H (0.56) | LTA4HHRH3ESR1KDM4EMEN1 | |
| SCHEMBL8915859 | 0.77 | LTA4H (0.54) | LTA4HHRH3ESR1KDM4EMEN1 | |
| SCHEMBL10576989 | 0.77 | KDM1A (0.38) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658951-A | ANTIESTROGENS, ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-08-19 | — | — | US | disclosed |