Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 10/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 6/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915859 | 0.95 | LTA4H (0.54) | LTA4HPSMB1PSMB5MEN1KMT2A | |
| SCHEMBL8917765 | 0.91 | LTA4H (0.56) | LTA4HMEN1KMT2AHRH3ESR1 | |
| SCHEMBL8916605 | 0.86 | LTA4H (0.56) | LTA4HMEN1KMT2AHRH3ESR1 | |
| SCHEMBL8915699 | 0.81 | LTA4H (0.58) | LTA4HPSMB1PSMB5MEN1KMT2A | |
| SCHEMBL8846067 | 0.80 | LTA4H (0.59) | LTA4HPSMB1PSMB5HRH3PSMB2 | |
| SCHEMBL10571615 | 0.79 | LTA4H (0.61) | LTA4HPSMB1PSMB5MEN1KMT2A | |
| SCHEMBL8915518 | 0.77 | LTA4H (0.55) | LTA4HPSMB1PSMB5MEN1KMT2A | |
| SCHEMBL5870409 | 0.76 | LTA4H (0.83) | LTA4HPSMB1PSMB5HRH3PSMB2 | |
| SCHEMBL3951411 | 0.76 | LTA4H (0.83) | LTA4HPSMB1PSMB5HRH3PSMB2 | |
| SCHEMBL10575062 | 0.75 | LTA4H (0.61) | LTA4HPSMB1PSMB5HRH3PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658951-A | ANTIESTROGENS, ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-08-19 | — | — | US | disclosed |