Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL779220 | 0.85 | NPC1 (0.56) | LMNAF2TSHRCES1ALDH1A1 | |
| SCHEMBL16340031 | 0.83 | CES2 (0.60) | ESR1ESR2CES1NPC1RAB9A | |
| SCHEMBL6937463 | 0.83 | MAPT (0.66) | MAPTTDP1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL8717537 | 0.80 | LMNA (0.67) | LMNAF2MAPTTDP1L3MBTL1 | |
| SCHEMBL9290961 | 0.79 | SRD5A2 (0.55) | ESR1ESR2TSHRTP53CES1 | |
| SCHEMBL23937279 | 0.79 | KMT2A (0.65) | LMNAESR1ESR2MAPTTDP1 | |
| SCHEMBL52413 | 0.78 | LMNA (0.70) | LMNAF2MAPTTDP1L3MBTL1 | |
| Hydrogen Peroxide SCHEMBL27952375 | 0.78 | LMNA (0.70) | LMNAF2MAPTTDP1L3MBTL1 | |
| Benzene SCHEMBL27793442 | 0.78 | LMNA (0.70) | LMNAF2MAPTTDP1L3MBTL1 | |
| SCHEMBL8928305 | 0.78 | CA1 (0.53) | LMNAESR1ESR2MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608013-A | Polyimides and thermosetting resin compositions containing the same | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0456515-B1 | Polyimides and thermosetting resin compositions containing the same | HITACHI CHEMICAL CO LTD (JP) | 1995-11-08 | — | — | EP | disclosed |
| EP-0456515-A1 | Polyimides and thermosetting resin compositions containing the same | Hitachi Chemical Co., Ltd. (JP) | 1991-11-13 | — | — | EP | disclosed |