Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 13/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 11/20 | 0.49 |
| ▸ | DRD2 | P14416 | 11/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920388 | 0.93 | MAPT (0.47) | HTR2ADRD4HTR1ADRD2MAPT | |
| SCHEMBL8916916 | 0.90 | HTR2A (0.42) | HTR2ADRD4HTR1ADRD2MAPT | |
| SCHEMBL8918049 | 0.84 | DRD2 (0.42) | HTR2ADRD4HTR1ADRD2ADRA1A | |
| SCHEMBL8916905 | 0.84 | MAPT (0.48) | HTR2AHTR1ADRD2MAPT | |
| SCHEMBL8919178 | 0.84 | HTR1A (0.41) | HTR2ADRD4HTR1ADRD2ADRA1A | |
| SCHEMBL8919069 | 0.83 | HTR1A (0.44) | HTR2AHTR1ADRD2ADRA1A | |
| SCHEMBL8918317 | 0.83 | HTR1A (0.46) | HTR2AHTR1ADRD2 | |
| SCHEMBL8916899 | 0.82 | HTR1A (0.41) | HTR2AHTR1ADRD2ADRA1A | |
| SCHEMBL8917989 | 0.80 | DRD2 (0.42) | HTR2AHTR1ADRD2 | |
| SCHEMBL8916474 | 0.80 | HTR1A (0.41) | HTR2AHTR1ADRD2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |