Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 18/20 | 0.42 |
| ▸ | HTR1A | P08908 | 17/20 | 0.42 |
| ▸ | HTR2A | P28223 | 15/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918317 | 0.90 | HTR1A (0.46) | DRD2HTR1AHTR2ASLC6A4 | |
| SCHEMBL8916474 | 0.86 | HTR1A (0.41) | DRD2HTR1AHTR2ASLC6A4HTR1D | |
| SCHEMBL8918028 | 0.85 | DRD2 (0.44) | DRD2HTR1AHTR2ASLC6A4 | |
| SCHEMBL8917225 | 0.84 | HTR1A (0.39) | DRD2HTR1AHTR2ASLC6A4HTR1D | |
| SCHEMBL8916905 | 0.83 | MAPT (0.48) | DRD2HTR1AHTR2ASLC6A4 | |
| SCHEMBL8916916 | 0.83 | HTR2A (0.42) | DRD2HTR1AHTR2A | |
| SCHEMBL8917721 | 0.81 | HTR1A (0.40) | DRD2HTR1AHTR2ASLC6A4HTR1D | |
| SCHEMBL8920388 | 0.80 | MAPT (0.47) | DRD2HTR1AHTR2A | |
| SCHEMBL8916967 | 0.80 | HTR2A (0.50) | DRD2HTR1AHTR2A | |
| SCHEMBL8919069 | 0.79 | HTR1A (0.44) | DRD2HTR1AHTR2ASLC6A4HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |