Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 3/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8920486 | 0.99 | CTSS (0.48) | CTSSDRD2SLC6A4TP53GAA | |
| SCHEMBL8916428 | 0.95 | CTSS (0.49) | CTSSDRD2SLC6A4TP53GAA | |
| SCHEMBL8915726 | 0.92 | CTSS (0.40) | CTSSDRD2SLC6A4TP53MAPT | |
| SCHEMBL8917783 | 0.91 | CTSS (0.50) | CTSSDRD2SLC6A4TP53GAA | |
| SCHEMBL8915757 | 0.90 | CTSS (0.51) | CTSSDRD2SLC6A4TP53GAA | |
| SCHEMBL8919123 | 0.87 | DRD2 (0.39) | CTSSDRD2SLC6A4TP53MAPT | |
| SCHEMBL8916920 | 0.87 | CTSS (0.41) | CTSSDRD2TP53GAAMAPT | |
| SCHEMBL8919136 | 0.86 | CTSS (0.40) | CTSSTP53GAAMAPTMCHR1 | |
| SCHEMBL8916994 | 0.86 | HTR2A (0.43) | CTSSDRD2TP53GAAMAPT | |
| SCHEMBL8916426 | 0.86 | MAPT (0.40) | CTSSDRD2SLC6A4TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |