Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29331520 | 0.83 | RXRA (0.51) | CFTRMAPTKDM4ECYP2C19ALDH1A1 | |
| SCHEMBL7474672 | 0.83 | RXRA (0.51) | MAPTKDM4ECES2CYP2C19ALDH1A1 | |
| SCHEMBL18075562 | 0.82 | IDO1 (0.50) | CFTRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL27757329 | 0.82 | ANO1 (0.49) | CFTRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL7472612 | 0.82 | CES2 (0.44) | CFTRMAPTKDM4ECES2CYP2C19 | |
| SCHEMBL15524663 | 0.81 | CFTR (0.43) | CFTRMAPTKDM4ECYP2C19ALDH1A1 | |
| SCHEMBL835012 | 0.81 | MAPT (0.51) | CFTRMAPTKDM4ECYP2C19ALDH1A1 | |
| SCHEMBL14453690 | 0.81 | CFTR (0.57) | CFTRMAPTKDM4ECYP2C19ALDH1A1 | |
| SCHEMBL996522 | 0.80 | CYP1A2 (0.58) | CFTRMAPTKDM4ECYP2C19ALDH1A1 | |
| SCHEMBL2858243 | 0.79 | CES2 (0.47) | CFTRMAPTKDM4ECES2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670525-A | Substituted 4-phenyl-6-amino-nicotinic acid compounds useful in the treatment of CNS disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |