Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CTH | P32929 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916767 | 0.86 | KDM5A (0.34) | KDM4EHSD17B10KMT2APOLBALDH1A1 | |
| SCHEMBL8917889 | 0.81 | CTH (0.34) | KDM4EHSD17B10CASP1KMT2AHTT | |
| SCHEMBL8919141 | 0.75 | CTH (0.31) | KDM4EKMT2APOLBALDH1A1MAPT | |
| SCHEMBL8916129 | 0.75 | MDM2 (0.34) | KDM4EKMT2AALDH1A1MAPTCTH | |
| SCHEMBL8916653 | 0.74 | SLC2A1 (0.36) | KDM4EKMT2AHTTSMN1; SMN2POLB | |
| SCHEMBL8917578 | 0.73 | ALDH1A1 (0.42) | KDM4EHSD17B10CASP1KMT2APOLB | |
| SCHEMBL20840578 | 0.71 | DDB1 (0.40) | KDM4EKMT2APOLBALDH1A1MAPT | |
| SCHEMBL29743006 | 0.71 | DDB1 (0.40) | KDM4EKMT2APOLBALDH1A1MAPT | |
| SCHEMBL8918459 | 0.69 | ALDH1A1 (0.36) | KDM4EHSD17B10KMT2APOLBALDH1A1 | |
| SCHEMBL27793412 | 0.69 | DDB1 (0.37) | KDM4EHSD17B10CASP1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686610-A | Pyridyl piperazine compound | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-11 | — | — | US | disclosed |