Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 10/20 | 0.39 |
| ▸ | HTR7 | P34969 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 10/20 | 0.38 |
| ▸ | DRD3 | P35462 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8916924 | 0.99 | CTSS (0.45) | CTSSHTR2AHTR7KCNH2DRD2 | |
| SCHEMBL8916164 | 0.95 | CTSS (0.48) | CTSSHTR2AHTR7KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL8918060 | 0.95 | CTSS (0.48) | CTSSHTR2AHTR7KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL8920342 | 0.90 | CTSS (0.49) | CTSSHTR2AHTR7KCNH2DRD2 | |
| SCHEMBL8917881 | 0.87 | CTSS (0.40) | CTSSHTR2ADRD2DRD3SLC6A4 | |
| SCHEMBL8916768 | 0.87 | CTSS (0.40) | CTSSHTR2ADRD2DRD3SLC6A4 | |
| Hydrochloric Acid SCHEMBL8917167 | 0.87 | CTSS (0.40) | CTSSHTR2ADRD2DRD3SLC6A4 | |
| SCHEMBL8916977 | 0.86 | CTSS (0.37) | CTSSHTR2ADRD2DRD3SLC6A4 | |
| SCHEMBL8920505 | 0.85 | CTSS (0.39) | CTSSHTR2ADRD2DRD3SLC6A4 | |
| Hydrochloric Acid SCHEMBL8920393 | 0.85 | CTSS (0.48) | CTSSHTR2AHTR7KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |