Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | DRD3 | P35462 | 5/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917985 | 0.94 | CTSS (0.40) | CTSSDRD2MAPTALDH1A1SLC6A4 | |
| SCHEMBL8917881 | 0.90 | CTSS (0.40) | CTSSDRD2SLC6A4MCHR1HTR2A | |
| SCHEMBL8916768 | 0.90 | CTSS (0.40) | CTSSDRD2MAPTMEN1KMT2A | |
| SCHEMBL8916164 | 0.90 | CTSS (0.48) | CTSSDRD2MAPTSLC6A4MCHR1 | |
| Hydrochloric Acid SCHEMBL8917167 | 0.90 | CTSS (0.40) | CTSSDRD2MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8918060 | 0.89 | CTSS (0.48) | CTSSDRD2MAPTSLC6A4MCHR1 | |
| SCHEMBL8919111 | 0.88 | DRD2 (0.51) | DRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL8916977 | 0.87 | CTSS (0.37) | CTSSDRD2MAPTSLC6A4POLB | |
| SCHEMBL8917017 | 0.86 | HTR2A (0.46) | DRD2SLC6A4HTR2ADRD3DRD4 | |
| SCHEMBL8916989 | 0.86 | DRD2 (0.38) | CTSSDRD2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |