SCHEMBL8917022

SCHEMBL8917022

COC(=O)c1cccc(C(=O)C(c2ccccc2)S(C)(=O)=O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.50
TSHR P16473 1/20 0.49
RAB9A P51151 1/20 0.47
CASR P41180 1/20 0.45
PPARA Q07869 1/20 0.45
ROCK2 O75116 1/20 0.44
ALDH1A1 P00352 4/20 0.44
GAA P10253 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PTGS2 P35354 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
SLC7A5 Q01650 1/20 0.43
LOXL2 Q9Y4K0 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
KDM4E B2RXH2 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8917404 0.85 ANPEP (0.43) ALDH1A1GAAL3MBTL1PTGS2CA12
Methyl Benzoate SCHEMBL28106657 0.77 TSHR (0.83) POLBTSHRRAB9AALDH1A1L3MBTL1
SCHEMBL34953 0.74 TSHR (0.70) POLBTSHRRAB9AALDH1A1CA12
SCHEMBL9562975 0.74 ALDH1A1 (0.49) RAB9AALDH1A1GAAL3MBTL1PTGS2
SCHEMBL316708 0.74 TSHR (0.53) POLBTSHRRAB9AALDH1A1GAA
SCHEMBL28566434 0.74 KMT2A (0.58) TSHRALDH1A1GAAPTGS2PTGS1
SCHEMBL6164364 0.74 TSHR (0.53) POLBTSHRRAB9AALDH1A1GAA
SCHEMBL27749717 0.74 TSHR (0.55) TSHRRAB9ACASRPPARAALDH1A1
Sulfuric Acid SCHEMBL27302538 0.73 POLB (0.62) POLBTSHRRAB9AALDH1A1CA12
SCHEMBL28454804 0.73 TSHR (0.58) POLBTSHRRAB9AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5670544-A ANTIISCHEMIC AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-23 US disclosed