Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917022 | 0.85 | POLB (0.50) | ALDH1A1GAAKDM4ECA1CA2 | |
| SCHEMBL9562975 | 0.79 | ALDH1A1 (0.49) | ALDH1A1GAATDP1KAT6ACYP3A4 | |
| SCHEMBL8431154 | 0.76 | SMN1; SMN2 (0.49) | ALDH1A1SRCTDP1KDM4EMEN1 | |
| SCHEMBL9997429 | 0.76 | SRC (0.43) | ALDH1A1GAASRCTDP1KDM4E | |
| SCHEMBL6069362 | 0.76 | ALDH1A1 (0.49) | ALDH1A1GAACYP3A4PTGS2SMN1; SMN2 | |
| SCHEMBL11605854 | 0.75 | CES2 (0.71) | ANPEPENPEPALDH1A1KMOTDP1 | |
| SCHEMBL11387985 | 0.75 | TDP1 (0.52) | ANPEPENPEPALDH1A1KMOSRC | |
| SCHEMBL6204480 | 0.74 | SRC (0.67) | ALDH1A1SRCKMT2APTGS2SMN1; SMN2 | |
| SCHEMBL11387982 | 0.73 | ANPEP (0.54) | ANPEPENPEPALDH1A1KMOTDP1 | |
| SCHEMBL317796 | 0.72 | CA12 (0.52) | ANPEPENPEPALDH1A1GAAKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670544-A | ANTIISCHEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |