Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431154 | 0.83 | SMN1; SMN2 (0.49) | ALDH1A1TDP1L3MBTL1CYP3A4CES2 | |
| SCHEMBL8917404 | 0.79 | ANPEP (0.43) | ALDH1A1TDP1L3MBTL1CYP3A4PTGS2 | |
| SCHEMBL23174036 | 0.76 | CES2 (0.67) | ALDH1A1TDP1L3MBTL1CES2LMNA | |
| SCHEMBL22673486 | 0.76 | ALDH1A1 (0.51) | ALDH1A1TDP1L3MBTL1CYP3A4CES2 | |
| SCHEMBL11756011 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TDP1L3MBTL1CYP3A4CES2 | |
| SCHEMBL8917022 | 0.74 | POLB (0.50) | ALDH1A1L3MBTL1CYP3A4PTGS2GAA | |
| SCHEMBL9997429 | 0.74 | SRC (0.43) | ALDH1A1TDP1L3MBTL1CYP3A4CES2 | |
| SCHEMBL30121859 | 0.71 | KMT2A (0.56) | ALDH1A1TDP1L3MBTL1CES2LMNA | |
| SCHEMBL28756340 | 0.71 | ACP3 (0.44) | TDP1L3MBTL1CES2LMNACES1 | |
| SCHEMBL29110180 | 0.71 | KMT2A (0.56) | ALDH1A1TDP1L3MBTL1CES2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538156-A1 | Fungicidal phenylpyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1993-04-21 | — | — | EP | disclosed |