Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412943 | 0.82 | GAA (0.51) | ALDH1A1SMN1; SMN2PKMKMT2AMAPT | |
| SCHEMBL18452191 | 0.81 | GAA (0.50) | ALDH1A1SMN1; SMN2PKMKMT2AMAPT | |
| SCHEMBL527544 | 0.80 | KMT2A (0.71) | ALDH1A1SMN1; SMN2PKMKMT2AMAPT | |
| SCHEMBL8816649 | 0.80 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2PKMKMT2AMAPT | |
| SCHEMBL1461897 | 0.79 | ELANE (0.60) | ALDH1A1SMN1; SMN2PKMKMT2AMAPT | |
| SCHEMBL1118843 | 0.78 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2PKMKMT2AMAPT | |
| SCHEMBL6322393 | 0.77 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2PKMKMT2AMAPT | |
| SCHEMBL20377184 | 0.77 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2PKMKMT2AMAPT | |
| SCHEMBL2233881 | 0.77 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2PKMKMT2AMAPT | |
| SCHEMBL9333093 | 0.76 | KMT2A (0.66) | ALDH1A1SMN1; SMN2PKMKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684018-A | Acyloxyisopropyl carbamates as prodrugs for amine drugs | MERCK & CO., INC. (US) | 1997-11-04 | — | — | US | disclosed |
| WO-1996018605-A1 | ACYLOXYISOPROPYL CARBAMATES AS PRODRUGS FOR AMINE DRUGS | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | disclosed |