Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917181 | 0.82 | HTR6 (0.34) | PRKDCKDM4EMAPTALDH1A1PHGDH | |
| SCHEMBL8918038 | 0.76 | ADORA2A (0.37) | PRKDCADRB1KDM4EL3MBTL1MAPT | |
| SCHEMBL1447600 | 0.72 | ADRB1 (0.62) | ADRB1KDM4EGAAL3MBTL1MAPT | |
| SCHEMBL217611 | 0.71 | ADRB1 (0.60) | ADRB1ALDH1A1HPGD | |
| SCHEMBL8917845 | 0.71 | KCNA3 (0.36) | KDM4ECES1CYP1A2CYP2A6 | |
| SCHEMBL8917269 | 0.70 | ADRB1 (0.34) | PRKDCADRB1KDM4EGAAL3MBTL1 | |
| SCHEMBL8917934 | 0.70 | MAPT (0.39) | PRKDCKDM4EMAPTALDH1A1PHGDH | |
| SCHEMBL8917729 | 0.70 | PRKDC (0.45) | PRKDCKDM4EMAPTALDH1A1PHGDH | |
| SCHEMBL1448499 | 0.69 | KDM4E (0.51) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL2607400 | 0.68 | CYP2A6 (0.48) | MAPTALDH1A1TDP1POLBCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |