Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916972 | 0.82 | MAPT (0.33) | MAPTTP53KDM4EL3MBTL1LMNA | |
| SCHEMBL8920541 | 0.76 | ADRB1 (0.34) | ADRB1MAPTTP53KDM4ELMNA | |
| SCHEMBL1447600 | 0.72 | ADRB1 (0.62) | ADRB1MAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL217611 | 0.71 | ADRB1 (0.60) | ADRB1LMNAHTTRECQLSMN1; SMN2 | |
| SCHEMBL8917168 | 0.70 | PRKDC (0.44) | ADRB1MAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL8917044 | 0.70 | MAPT (0.48) | MAPTTP53LMNARECQLALDH1A1 | |
| SCHEMBL8918997 | 0.70 | DRD2 (0.35) | CYP1A2CYP2A6 | |
| SCHEMBL8919052 | 0.70 | MAPT (0.58) | MAPTTP53LMNARECQLALDH1A1 | |
| SCHEMBL1448499 | 0.69 | KDM4E (0.51) | MAPTKDM4EGAAL3MBTL1LMNA | |
| SCHEMBL8404365 | 0.68 | CYP1A2 (0.48) | MAPTGAACYP1A2CYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |