Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 10/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915283 | 1.00 | FDPS (0.45) | FDPSSMPD1CFTRPTPN1POLB | |
| SCHEMBL7616372 | 0.77 | CYP1A2 (0.33) | — | |
| SCHEMBL8816757 | 0.74 | S1PR2 (0.34) | — | |
| SCHEMBL437990 | 0.72 | MAOA (0.43) | — | |
| Hydrochloric Acid SCHEMBL17261331 | 0.71 | MAOA (0.42) | POLB | |
| SCHEMBL7391478 | 0.71 | — | — | |
| SCHEMBL8916429 | 0.71 | FDPS (0.55) | FDPSSMPD1 | |
| SCHEMBL8918695 | 0.71 | FDPS (0.55) | FDPSSMPD1 | |
| SCHEMBL8915544 | 0.70 | CA9 (0.38) | FDPSCFTR | |
| SCHEMBL11368813 | 0.70 | HDAC3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624917-A | Method of inhibiting squalene synthetase | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-29 | — | — | US | claimed |