Methacrylic Acid

Methacrylic Acid

SCHEMBL8917320

C=C(C)C(=O)O.C=CC(=O)OCCCC.O=S(=O)(O)C=Cc1ccccc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.49
HPGD P15428 1/20 0.49
TDP1 Q9NUW8 2/20 0.42
THRB P10828 1/20 0.40
PPARG P37231 2/20 0.40
KDM4E B2RXH2 2/20 0.40
AKR1B10 O60218 1/20 0.39
AKR1B1 P15121 1/20 0.39
APP P05067 1/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
EGFR P00533 1/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP3A4 P08684 1/20 0.36
BCHE P06276 1/20 0.36
ALOX5 P09917 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL8971128 0.90 HPGD (0.50) TSHRHPGDTDP1THRBPPARG
Maleic Acid SCHEMBL8971121 0.90 HPGD (0.50) TSHRHPGDTDP1THRBPPARG
Styrene SCHEMBL1085645 0.88 TSHR (0.50) TSHRHPGDTDP1THRBKDM4E
Styrene SCHEMBL1563744 0.85 TSHR (0.58) TSHRHPGDTDP1THRBKDM4E
Styrene SCHEMBL5546418 0.83 TSHR (0.56) TSHRHPGDTDP1THRBKDM4E
Styrene SCHEMBL3915927 0.82 TSHR (0.55) TSHRHPGDTDP1THRBKDM4E
Methacrylic Acid SCHEMBL12490542 0.82 TSHR (0.49) TSHRHPGDTDP1THRBKDM4E
Juarezic Acid SCHEMBL2878619 0.82 HPGD (0.49) TSHRHPGDTDP1THRBKDM4E
Methacrylic Acid SCHEMBL7074260 0.82 TSHR (0.69) TSHRHPGDTHRBALDH1A1CYP3A4
Styrene SCHEMBL15770166 0.81 TSHR (0.54) TSHRHPGDTDP1THRBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5604083-A BLEND OF ELECTROCONDUCTIVE POLYMER AND OXAZOLINE POLYMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-02-18 US disclosed