Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 3/20 | 0.33 |
| ▸ | CPT2 | P23786 | 2/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940 | 0.89 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL8721139 | 0.87 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL20973099 | 0.87 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL10797042 | 0.87 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL11405967 | 0.87 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL2770806 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL330107 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| Inositol SCHEMBL2519274 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| Citric Acid SCHEMBL73266 | 0.77 | ALDH1A1 (0.79) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| Citric Acid SCHEMBL332489 | 0.77 | ALDH1A1 (0.79) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639439-A | Gallium dimercaptosuccinate as a novel tumor imaging agent | INSTITUTE OF NUCLEAR ENERGY RESEARCH, TAIWAN (TW) | 1997-06-17 | — | — | US | disclosed |