Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA4 | P22748 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917700 | 0.89 | CYP1A2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL8918086 | 0.89 | PTGS2 (0.48) | PTGS2CA1CA2CA9CA4 | |
| SCHEMBL9229049 | 0.87 | PTGS2 (0.55) | PTGS2PTGS1PDPK1KEAP1 | |
| SCHEMBL7651780 | 0.85 | PTGS2 (0.54) | PTGS2CA1CA2CA9CA4 | |
| SCHEMBL8918143 | 0.84 | PTGS2 (0.54) | PTGS2CA1CA2CA9CA4 | |
| SCHEMBL9233871 | 0.83 | PDPK1 (0.60) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL9233734 | 0.82 | PTGS2 (0.57) | PTGS2CA1CA2CA9CA4 | |
| SCHEMBL8916655 | 0.79 | CYP1A2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL8917480 | 0.79 | PTGS2 (0.49) | PTGS2PTGS1PDPK1 | |
| SCHEMBL8918841 | 0.76 | PTGS2 (0.48) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |