Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917478 | 0.89 | CYP1A2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL9233871 | 0.84 | PDPK1 (0.60) | PTGS2PTGS1PDPK1 | |
| SCHEMBL8917786 | 0.82 | PTGS2 (0.40) | PTGS2PTGS1PDPK1 | |
| SCHEMBL7651780 | 0.82 | PTGS2 (0.54) | PTGS2PTGS1PDPK1 | |
| SCHEMBL9229049 | 0.81 | PTGS2 (0.55) | PTGS2PTGS1PDPK1 | |
| SCHEMBL8917361 | 0.79 | PTGS2 (0.56) | PTGS2PTGS1PDPK1 | |
| SCHEMBL9233734 | 0.78 | PTGS2 (0.57) | PTGS2PTGS1PDPK1 | |
| SCHEMBL8918086 | 0.75 | PTGS2 (0.48) | PTGS2PTGS1PDPK1 | |
| SCHEMBL9091738 | 0.75 | PTGS2 (0.58) | PTGS2PTGS1PDPK1 | |
| SCHEMBL7649968 | 0.74 | PTGS2 (0.53) | PTGS2PTGS1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |