Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 6/20 | 0.67 |
| ▸ | MC3R | P41968 | 4/20 | 0.67 |
| ▸ | MC5R | P33032 | 4/20 | 0.67 |
| ▸ | CCKBR | P32239 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | AGER | Q15109 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MC1R | Q01726 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9439245 | 0.99 | MC4R (0.65) | MC4RMC3RMC5RCCKBRHTR2A | |
| Hydrochloric Acid SCHEMBL9439526 | 0.83 | MC4R (0.57) | MC4RMC3RMC5R | |
| SCHEMBL8917376 | 0.83 | MC4R (0.60) | MC4RMC3RMC5R | |
| SCHEMBL24785636 | 0.80 | MC4R (0.56) | MC4RMC3RMC5R | |
| Hydrochloric Acid SCHEMBL9439232 | 0.79 | SLC7A5 (0.50) | MC4RMC3RMC5RHTR2C | |
| SCHEMBL20815135 | 0.78 | MC4R (0.58) | MC4RMC3RMC5RHTR2AHTR2C | |
| SCHEMBL20815138 | 0.78 | MC4R (0.58) | MC4RMC3RMC5RHTR2AHTR2C | |
| SCHEMBL9572329 | 0.78 | MC4R (0.55) | MC4RMC3RMC5R | |
| Hydrochloric Acid SCHEMBL9535635 | 0.78 | LTA4H (0.50) | MC4RMC3RMC5R | |
| SCHEMBL29036894 | 0.78 | AGER (0.48) | MC4RMC3RMC5RHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000725-A2 | AMINO ACID ANALOG CCK ANTAGONISTS | ABBOTT LABORATORIES (US) | 1991-01-24 | — | — | WO | disclosed |