Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.86 |
| ▸ | ELANE | P08246 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6598757 | 0.88 | KMT2A (0.66) | KMT2AELANEMAOBRAB9ANPC1 | |
| SCHEMBL12110126 | 0.87 | KMT2A (0.67) | KMT2AELANEMAOBRAB9ANPC1 | |
| SCHEMBL13940472 | 0.84 | KMT2A (0.68) | KMT2AMAPTMEN1TDP2CDC25B | |
| SCHEMBL13151876 | 0.84 | KMT2A (0.71) | KMT2AELANEMAOBRAB9ANPC1 | |
| SCHEMBL12108751 | 0.80 | KMT2A (0.66) | KMT2AELANEMAOBRAB9ANPC1 | |
| SCHEMBL16601623 | 0.79 | TDP2 (0.66) | KMT2AMEN1TDP2CDC25BPDK2 | |
| SCHEMBL7807992 | 0.78 | KMT2A (0.54) | KMT2AMAOBRAB9ANPC1PKM | |
| SCHEMBL17339870 | 0.75 | KMT2A (0.51) | KMT2AMAOBRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL19856524 | 0.74 | KMT2A (0.50) | KMT2AMAOBRAB9ANPC1PKM | |
| SCHEMBL13168840 | 0.74 | KMT2A (0.54) | KMT2AELANEMAOBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605905-A | DIAZAQUINOMICIN ANALOGS | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 1997-02-25 | — | — | US | disclosed |
| EP-0574195-A1 | Antitumoral aza- and diazaanthracenes | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 1993-12-15 | — | — | EP | disclosed |