Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | DTYMK | P23919 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.42 |
| ▸ | F13A1 | P00488 | 3/20 | 0.40 |
| ▸ | TGM2 | P21980 | 3/20 | 0.40 |
| ▸ | TGM1 | P22735 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985778 | 0.82 | POLB (0.50) | POLBACHEDTYMKGPR119CKS1B | |
| SCHEMBL20818668 | 0.73 | POLB (0.50) | POLBACHEDTYMKGPR119MEN1 | |
| SCHEMBL30476354 | 0.73 | POLB (0.50) | POLBACHEDTYMKGPR119MEN1 | |
| SCHEMBL7402298 | 0.72 | ALDH1A1 (0.52) | POLBACHEDTYMKGPR119ALDH1A1 | |
| SCHEMBL30476397 | 0.71 | POLB (0.50) | POLBACHEDTYMKGPR119MEN1 | |
| SCHEMBL20818148 | 0.71 | POLB (0.50) | POLBACHEDTYMKGPR119MEN1 | |
| SCHEMBL8923840 | 0.71 | ACHE (0.48) | POLBACHEDTYMKGPR119MEN1 | |
| SCHEMBL31652019 | 0.71 | POLB (0.55) | POLBACHEDTYMKGPR119CKS1B | |
| SCHEMBL11366665 | 0.70 | POLB (0.54) | POLBACHEDTYMKGPR119CKS1B | |
| SCHEMBL21358044 | 0.70 | KDM4E (0.39) | MEN1ALDH1A1LMNAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686610-A | Pyridyl piperazine compound | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-11 | — | — | US | disclosed |
| US-5599930-A | Substituted indoles as anti-AIDS pharmaceuticals | THE UPJOHN COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1993001181-A1 | SUBSTITUTED INDOLES AS ANTI-AIDS PHARMACEUTICALS | THE UPJOHN COMPANY (US) | 1993-01-21 | — | — | WO | disclosed |