Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | ACP1 | P24666 | 1/20 | 0.52 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 3/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920728 | 0.88 | ALDH1A1 (0.45) | PTPRBPTPN1ACP1PPIDCYP19A1 | |
| SCHEMBL5661041 | 0.85 | ALDH1A1 (0.55) | PTPRBPTPN1ACP1PPIDTSHR | |
| SCHEMBL7442766 | 0.83 | PTPRB (0.46) | PTPRBPTPN1ACP1PPIDCYP19A1 | |
| SCHEMBL1677466 | 0.78 | MMP8 (0.57) | PTPRBPPIDCYP19A1TSHRALDH1A1 | |
| SCHEMBL8331685 | 0.76 | CYP19A1 (0.44) | PTPRBCYP19A1TSHRALDH1A1KMT2A | |
| SCHEMBL3309782 | 0.75 | PTPN1 (0.48) | PTPRBPTPN1ACP1PPIDALDH1A1 | |
| SCHEMBL3312228 | 0.75 | PTPN1 (0.48) | PTPRBPTPN1ACP1PPIDTSHR | |
| SCHEMBL10992850 | 0.75 | GAA (0.50) | PTPRBPTPN1ACP1TSHRALDH1A1 | |
| SCHEMBL304656 | 0.74 | CYP19A1 (0.63) | PPIDCYP19A1TSHRCDC7DBF4 | |
| SCHEMBL4419400 | 0.73 | ALDH1A1 (0.62) | PTPRBPTPN1PPIDTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658935-A | USEFUL AS INHIBITORS OF THROMBOCYTE AGGREGATION, THE METASTASIS OF CARCINOMA CELLS AND THE BINDING OF OSTEOCLASTS ON BONE SURFACES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |