Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTPRB | P23467 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 5/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917735 | 0.88 | PTPRB (0.52) | ALDH1A1LMNAPTPRBRECQLMMP8 | |
| SCHEMBL3959617 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAPTPRBRECQLMMP8 | |
| SCHEMBL7442766 | 0.80 | PTPRB (0.46) | ALDH1A1LMNAPTPRBRECQLMMP8 | |
| SCHEMBL1677466 | 0.78 | MMP8 (0.57) | ALDH1A1PTPRBRECQLMMP8CDC7 | |
| SCHEMBL3278323 | 0.78 | ALDH1A1 (0.47) | ALDH1A1LMNAPTPRBRECQLMMP8 | |
| SCHEMBL3278579 | 0.77 | ALDH1A1 (0.49) | ALDH1A1LMNAPTPRBRECQLMMP8 | |
| SCHEMBL8331685 | 0.76 | CYP19A1 (0.44) | ALDH1A1PTPRBPOLBCYP19A1KMT2A | |
| SCHEMBL4419400 | 0.76 | ALDH1A1 (0.62) | ALDH1A1LMNAPTPRBRECQLMMP8 | |
| SCHEMBL5661041 | 0.76 | ALDH1A1 (0.55) | ALDH1A1LMNAPTPRBRECQLMMP8 | |
| SCHEMBL3309786 | 0.75 | ALDH1A1 (0.44) | ALDH1A1LMNAPTPRBRECQLMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658935-A | USEFUL AS INHIBITORS OF THROMBOCYTE AGGREGATION, THE METASTASIS OF CARCINOMA CELLS AND THE BINDING OF OSTEOCLASTS ON BONE SURFACES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |