SCHEMBL8917808

SCHEMBL8917808

CC1OC2(NC(=N)c3cccc(Oc4ccccc4)c32)O1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.35
SLC6A4 P31645 4/20 0.35
HTR1A P08908 3/20 0.35
SLC6A3 Q01959 3/20 0.35
PTGS2 P35354 1/20 0.35
BRD4 O60885 8/20 0.35
NCOA1 Q15788 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
ELANE P08246 1/20 0.32
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
XBP1 P17861 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HKDC1 Q2TB90 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8917800 0.81 SLC6A2 (0.35) SLC6A2SLC6A4HTR1ASLC6A3PTGS2
SCHEMBL8917739 0.81 SLC6A2 (0.35) SLC6A2SLC6A4HTR1ASLC6A3BRD4
SCHEMBL8922193 0.77 CYP1A2 (0.38) ELANELMNATP53POLBMAPT
SCHEMBL8922917 0.76 DAO (0.31)
SCHEMBL8921050 0.75 MAOB (0.40) SLC6A2SLC6A4SLC6A3MAPT
SCHEMBL7828729 0.75 ALDH1A1 (0.36) SLC6A2SLC6A4HTR1ASLC6A3PTGS2
SCHEMBL8919048 0.75 PDE5A (0.36) SLC6A3LMNAMAPTKMT2A
SCHEMBL8920291 0.73
SCHEMBL7826158 0.72 LTA4H (0.35) SLC6A2SLC6A4PTGS2BRD4NCOA1
SCHEMBL8919068 0.68 SLC6A2 (0.32) SLC6A2SLC6A4HTR1ASLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed