SCHEMBL8922193

SCHEMBL8922193

CCCCOc1cccc2c1C1(NC2=N)OC(C)O1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
CYP19A1 P11511 1/20 0.38
PDE5A O76074 3/20 0.34
PDE4A P27815 3/20 0.34
PDE4B Q07343 3/20 0.34
PDE4C Q08493 3/20 0.34
PDE4D Q08499 3/20 0.34
TP53 P04637 3/20 0.33
CNR2 P34972 3/20 0.33
ELANE P08246 1/20 0.33
MCHR1 Q99705 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
KDM4E B2RXH2 1/20 0.32
GCGR P47871 2/20 0.32
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8919048 0.95 PDE5A (0.36) CYP1A2CYP2C9CYP2C19CYP19A1PDE5A
SCHEMBL8918266 0.95 PDE5A (0.36) CYP1A2CYP2C9CYP2C19CYP19A1PDE5A
SCHEMBL8920492 0.94 CYP2A6 (0.34) CYP1A2CYP2C9CYP2C19CYP19A1PDE5A
SCHEMBL8919959 0.88 ALDH1A1 (0.34) MAPTKDM4E
SCHEMBL8919517 0.81 PRKCA (0.38) CYP1A2CYP2C9CYP2C19CYP19A1TP53
SCHEMBL8920603 0.81 ACHE (0.35) LMNAKDM4E
SCHEMBL8918262 0.79 PDE5A (0.37) CYP1A2CYP2C9CYP2C19CYP19A1PDE5A
SCHEMBL8919042 0.79 PDE5A (0.37) CYP1A2CYP2C9CYP2C19CYP19A1PDE5A
SCHEMBL8919755 0.77 PRKCA (0.43) CYP1A2CYP2C9CYP2C19PDE5APDE4A
SCHEMBL8919135 0.77 PRKCA (0.43) CYP1A2CYP2C9CYP2C19PDE5APDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed