Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2832485 | 0.85 | APP (0.44) | PPARGPPARAIDO1 | |
| SCHEMBL8919411 | 0.84 | TRPA1 (0.36) | TRPA1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL8719986 | 0.84 | CA1 (0.43) | PPARAKDM4EKMT2A | |
| SCHEMBL14453298 | 0.84 | SIGMAR1 (0.34) | PPARGPPARASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3428434 | 0.81 | ADRB2 (0.40) | TRPA1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL3428431 | 0.81 | ADRB2 (0.40) | TRPA1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL5788640 | 0.78 | EPHX1 (0.50) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL1228897 | 0.78 | — | — | |
| SCHEMBL4698511 | 0.78 | CYP1A2 (0.54) | CYP1A2 | |
| SCHEMBL6349630 | 0.77 | CSNK1E (0.47) | TRPA1SLC6A2TAAR1MAOASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686565-A | ANTIINFLAMMATORY AGENTS | SCIOS INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5552383-A | ANALGESIC, ANTIINFLAMMATORY FOR WOUNDS | SCIOS NOVA INC. (US) | 1996-09-03 | — | — | US | disclosed |