Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.48 |
| ▸ | DRD4 | P21917 | 11/20 | 0.48 |
| ▸ | DRD3 | P35462 | 8/20 | 0.48 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545430 | 0.87 | DRD4 (0.49) | DRD2DRD4DRD3HTR1ASIGMAR1 | |
| SCHEMBL8551090 | 0.86 | DRD2 (0.48) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL8917850 | 0.69 | HTR1A (0.40) | DRD2DRD4DRD3HTR1ASLC6A4 | |
| SCHEMBL8917837 | 0.67 | HTR1A (0.37) | DRD2DRD4DRD3HTR1ASLC6A4 | |
| SCHEMBL5564087 | 0.65 | DRD2 (0.50) | DRD2DRD4DRD3HTR1ASIGMAR1 | |
| SCHEMBL18872185 | 0.64 | HTR1A (0.53) | DRD2DRD4DRD3HTR1ASIGMAR1 | |
| SCHEMBL6214207 | 0.63 | HTR1A (0.48) | DRD2DRD3HTR1ASIGMAR1SLC6A4 | |
| SCHEMBL5563918 | 0.63 | HTR1A (0.52) | DRD2DRD4DRD3HTR1ASIGMAR1 | |
| SCHEMBL5568304 | 0.63 | HTR1A (0.52) | DRD2DRD4DRD3HTR1ASIGMAR1 | |
| SCHEMBL6214213 | 0.62 | DRD2 (0.50) | DRD2DRD3HTR1ASIGMAR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668148-A | BENIGN PROSTATIC HYPERTROPHY | MERCK & CO., INC. (US) | 1997-09-16 | — | — | US | disclosed |