Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 7/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545428 | 0.87 | ADRA1D (0.39) | HTR1ASLC6A4DRD2DRD4DRD3 | |
| SCHEMBL8917850 | 0.86 | HTR1A (0.40) | HTR1ASLC6A4DRD2DRD4DRD3 | |
| SCHEMBL8551088 | 0.86 | HTR2A (0.42) | HTR1ADRD2DRD4DRD3HTR2A | |
| SCHEMBL8545434 | 0.72 | DRD2 (0.40) | HTR1ASLC6A4DRD2DRD4DRD3 | |
| SCHEMBL8546423 | 0.71 | SNCA (0.42) | HTR1ASLC6A4DRD2DRD4DRD3 | |
| SCHEMBL8551091 | 0.71 | HTR1A (0.53) | HTR1ADRD2HTR2A | |
| SCHEMBL8549889 | 0.69 | SLC6A4 (0.44) | HTR1ASLC6A4DRD2DRD4DRD3 | |
| SCHEMBL8549271 | 0.68 | DRD2 (0.42) | HTR1ASLC6A4DRD2DRD4DRD3 | |
| SCHEMBL8550715 | 0.67 | HTR1A (0.47) | HTR1ASLC6A4DRD2DRD4DRD3 | |
| SCHEMBL8917842 | 0.67 | DRD2 (0.48) | HTR1ASLC6A4DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668148-A | BENIGN PROSTATIC HYPERTROPHY | MERCK & CO., INC. (US) | 1997-09-16 | — | — | US | disclosed |