Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014454 | 0.80 | NPC1 (0.42) | NPC1L3MBTL1HTTSMN1; SMN2MAPT | |
| SCHEMBL1828048 | 0.79 | L3MBTL1 (0.41) | NPC1L3MBTL1HTTSMN1; SMN2MAPT | |
| SCHEMBL9178594 | 0.79 | L3MBTL1 (0.46) | NPC1L3MBTL1HTTSMN1; SMN2MAPT | |
| SCHEMBL6938598 | 0.76 | L3MBTL1 (0.39) | NPC1L3MBTL1HTTSMN1; SMN2MAPT | |
| SCHEMBL29091452 | 0.76 | NPC1 (0.40) | NPC1L3MBTL1HTTSMN1; SMN2MAPT | |
| SCHEMBL2805922 | 0.76 | NPC1 (0.40) | NPC1L3MBTL1HTTSMN1; SMN2MAPT | |
| SCHEMBL7851780 | 0.76 | L3MBTL1 (0.41) | NPC1L3MBTL1HTTSMN1; SMN2MAPT | |
| SCHEMBL29067489 | 0.75 | NPC1 (0.41) | NPC1L3MBTL1HTTSMN1; SMN2MAPT | |
| SCHEMBL4621722 | 0.74 | NPC1 (0.40) | NPC1L3MBTL1HTTSMN1; SMN2MAPT | |
| SCHEMBL10959754 | 0.74 | NPC1 (0.40) | NPC1L3MBTL1HTTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684131-A | Substituted benzhydrylamines as handles for solid phase peptide synthesis | LEBL MICHAL (US) | 1997-11-04 | — | — | US | disclosed |