Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8146904 | 0.87 | ALDH1A1 (0.54) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL27185351 | 0.85 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL17744425 | 0.82 | ALDH1A1 (0.47) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9461987 | 0.81 | GRIN2D (0.52) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL10984988 | 0.80 | GPR35 (0.47) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL10977432 | 0.80 | TDP1 (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6701537 | 0.80 | TSHR (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL28043007 | 0.79 | MAPK1 (0.49) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9461274 | 0.78 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9461403 | 0.78 | MAPT (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4865619-A | Use, as a coupler, of 2,4-diamino-1,3-dimethoxybenzene or one of its salts, in combination with oxidation dye precursors, for dyeing human hair, hair dyeing composition containing the said coupler and process for preparing the said coupler | L'OREAL (FR) | 1989-09-12 | — | — | US | claimed |
| JP-9118656-A | — | — | None | — | — | JP | disclosed |
| JP-1063508-A | — | — | None | — | — | JP | disclosed |
| JP-H09118656-A | PRODUCTION OF 2,4-DIAMINO-1,3-DIMETHOXYBENZENE | L'OREAL SA | 1997-05-06 | — | — | JP | disclosed |
| US-RE34300-E | Hair dye | L'OREAL (FR) | 1993-07-06 | — | — | US | disclosed |
| EP-0295474-B1 | CHLOROMETAPHENYLENEDIAMINES, THEIR USE AS COUPLING AGENTS IN OXYDATION COLOURING OF KERATINIC FIBRES, COLOURITY COMPOSITIONS FOR HAIR CONTAINING THESE COMPOUNDS AND COLOURING PROCESS USING THESE COMPOSITIONS | L'OREAL (FR) | 1991-07-17 | — | — | EP | disclosed |
| EP-0294669-B1 | METAPHENYLENDIAMINES, PROCESS FOR THEIR PREPARATION, INTERMEDIATE COMPOUNDS AND USE OF THESE METAPHENYLENDIAMINES AS COUPLERS IN OXYDATIVE COLOURING OF KERATINIC FIBRES ESPECIALLY OF HUMAN HAIR | L'OREAL (FR) | 1991-07-17 | — | — | EP | disclosed |
| US-5015772-A | Hair dyes | L'OREAL (FR) | 1991-05-14 | — | — | US | disclosed |
| US-4960432-A | Meta-phenylenediamines, process for preparation thereof, intermediate compounds and use of these meta-phenylenediamines as couplers for the oxidation dyeing of keratinous fibres and especially human hair | L'OREAL (FR) | 1990-10-02 | — | — | US | disclosed |
| US-4865619-A | Use, as a coupler, of 2,4-diamino-1,3-dimethoxybenzene or one of its salts, in combination with oxidation dye precursors, for dyeing human hair, hair dyeing composition containing the said coupler and process for preparing the said coupler | L'OREAL (FR) | 1989-09-12 | — | — | US | disclosed |
| US-4865618-A | New chloro-meta-phenylenediamines, their use as couplers in the oxidation dyeing of keratinous fibres, dyeing compositions for hair containing these compounds and dyeing process using the said | L'OREAL (FR) | 1989-09-12 | — | — | US | disclosed |
| JP-S6463508-A | MANUFACTURE OF 2,4-DIAMINO-1,3-DIMETHOXYBENZENE AND HAIR DYE COMPOSITION | OREAL | 1989-03-09 | — | — | JP | disclosed |
| EP-0295474-A1 | Chlorometaphenylenediamines, their use as coupling agents in oxydation colouring of keratinic fibres, colourity compositions for hair containing these compounds and colouring process using these compositions | L'OREAL (FR) | 1988-12-21 | — | — | EP | disclosed |
| EP-0294669-A1 | Metaphenylendiamines, process for their preparation, intermediate compounds and use of these metaphenylendiamines as couplers in oxydative colouring of keratinic fibres especially of human hair | L'OREAL (FR) | 1988-12-14 | — | — | EP | disclosed |