Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 18/20 | 0.49 |
| ▸ | DRD3 | P35462 | 11/20 | 0.49 |
| ▸ | HTR7 | P34969 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917651 | 0.92 | HTR2A (0.40) | HTR2ADRD3HTR7KCNH2DRD2 | |
| SCHEMBL8918089 | 0.91 | DRD2 (0.54) | HTR2ADRD3HTR7KCNH2DRD2 | |
| SCHEMBL8918426 | 0.89 | HTR2A (0.44) | HTR2ADRD3HTR7KCNH2DRD2 | |
| SCHEMBL8917038 | 0.89 | HTR2A (0.50) | HTR2ADRD3HTR7KCNH2DRD2 | |
| SCHEMBL8917017 | 0.87 | HTR2A (0.46) | HTR2ADRD3KCNH2DRD2HTR1A | |
| SCHEMBL8915767 | 0.86 | HTR2A (0.38) | HTR2ADRD3HTR7KCNH2DRD2 | |
| SCHEMBL8920271 | 0.86 | DRD2 (0.56) | HTR2ADRD3HTR7KCNH2DRD2 | |
| Oxalic Acid SCHEMBL8916497 | 0.85 | DRD2 (0.45) | HTR2AHTR7KCNH2DRD2HTR1A | |
| SCHEMBL8917101 | 0.85 | DRD2 (0.54) | HTR2ADRD3HTR7KCNH2DRD2 | |
| SCHEMBL8916743 | 0.85 | HTR2A (0.51) | HTR2ADRD3HTR7KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |