Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772672 | 0.74 | MMP13 (0.44) | ALDH1A1SMN1; SMN2HTTLMNAKMT2A | |
| SCHEMBL8592554 | 0.74 | MMP13 (0.44) | ALDH1A1SMN1; SMN2HTTLMNAKMT2A | |
| SCHEMBL8592547 | 0.74 | MMP13 (0.44) | ALDH1A1SMN1; SMN2HTTLMNAKMT2A | |
| SCHEMBL8921289 | 0.67 | TDP1 (0.45) | TDP1ALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL21828917 | 0.65 | CA12 (0.51) | ALDH1A1SMN1; SMN2POLBHTTLMNA | |
| SCHEMBL13264862 | 0.63 | ALDH1A1 (0.47) | TDP1ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL10841951 | 0.63 | ALDH1A1 (0.41) | TDP1ALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL8919982 | 0.63 | MMP13 (0.46) | TDP1ALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL28346527 | 0.62 | HTT (0.47) | ALDH1A1SMN1; SMN2POLBHTTLMNA | |
| SCHEMBL8903680 | 0.62 | KMT2A (0.58) | ALDH1A1SMN1; SMN2POLBLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691349-A | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |