Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921229 | 0.87 | ATM (0.43) | ALDH1A1SMN1; SMN2POLBRAB9AMAPK1 | |
| SCHEMBL8918777 | 0.81 | TDP1 (0.37) | TDP1ALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL8918772 | 0.81 | ALDH1A1 (0.39) | TDP1ALDH1A1SMN1; SMN2RAB9AHTT | |
| SCHEMBL8919905 | 0.79 | FDFT1 (0.41) | TDP1ALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL927512 | 0.77 | CA12 (0.51) | MMP13TDP1ALDH1A1RAB9AHTT | |
| SCHEMBL8920052 | 0.76 | KMT2A (0.53) | ALDH1A1SMN1; SMN2GAARAB9AHPGD | |
| SCHEMBL17996034 | 0.75 | FFAR1 (0.51) | MMP13TDP1ALDH1A1POLBRAB9A | |
| SCHEMBL6365625 | 0.73 | CA1 (0.66) | TDP1ALDH1A1SMN1; SMN2RAB9AHTT | |
| SCHEMBL8921289 | 0.72 | TDP1 (0.45) | TDP1ALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL8707234 | 0.71 | HRH3 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691349-A | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |