SCHEMBL8918299

SCHEMBL8918299

CCOc1ccc2c(c1)C1(NC2=N)OC(C)O1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.38
ALDH1A1 P00352 5/20 0.36
LMNA P02545 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
CYP3A4 P08684 2/20 0.36
HPGD P15428 2/20 0.36
HSD17B10 Q99714 2/20 0.36
ALOX12 P18054 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALOX15 P16050 1/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
OPRM1 P35372 2/20 0.36
OPRD1 P41143 2/20 0.36
OPRK1 P41145 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8920583 0.90 PDK2 (0.40) PDK2ALDH1A1LMNAMEN1KMT2A
SCHEMBL8919076 0.90 PDK2 (0.40) PDK2ALDH1A1MEN1KMT2AMAPT
SCHEMBL8919289 0.90 ALDH1A1 (0.39) PDK2ALDH1A1LMNATDP1MEN1
SCHEMBL8920315 0.87 PDK2 (0.43) PDK2LMNATDP1CYP3A4KDM4E
SCHEMBL8918861 0.87 PDK2 (0.43) PDK2LMNATDP1CYP3A4KDM4E
SCHEMBL8919366 0.83 PDK2 (0.34) PDK2
SCHEMBL8918297 0.83 PDK2 (0.39) PDK2ALDH1A1LMNATDP1MEN1
SCHEMBL8918854 0.81 MAOA (0.40) PDK2LMNATDP1POLBTP53
SCHEMBL8920374 0.80 KMT2A (0.36) PDK2ALDH1A1LMNAMEN1KMT2A
SCHEMBL8919249 0.80 MEN1 (0.36) PDK2ALDH1A1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed