Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401151 | 0.90 | ALDH1A1 (0.47) | ALDH1A1GAACASP1NPSR1NPC1 | |
| SCHEMBL9129459 | 0.84 | MEN1 (0.38) | ALDH1A1CASP1MAPTMEN1KMT2A | |
| Bicarbonate SCHEMBL8397677 | 0.77 | ALDH1A1 (0.58) | ALDH1A1GAACASP1NPC1RAB9A | |
| SCHEMBL9487720 | 0.77 | ALDH1A1 (0.61) | ALDH1A1GAANPSR1NPC1RAB9A | |
| SCHEMBL20858637 | 0.77 | ALDH1A1 (0.61) | ALDH1A1GAANPSR1NPC1RAB9A | |
| SCHEMBL8918344 | 0.74 | ALDH1A1 (0.43) | ALDH1A1GAACASP1NPSR1NPC1 | |
| SCHEMBL29398811 | 0.73 | CASP1 (0.47) | ALDH1A1GAACASP1NPSR1MAPT | |
| SCHEMBL4680857 | 0.72 | CASP1 (0.45) | CASP1MAPTMEN1KMT2A | |
| SCHEMBL19672930 | 0.71 | MEN1 (0.38) | ALDH1A1CASP1MAPTMEN1KMT2A | |
| SCHEMBL27814238 | 0.69 | ABCC4 (0.62) | ALDH1A1GAAMAPTLMNAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625059-A | Process for the manufacture of 4-acetoxy-3-hydroxyethyl-azetidinone | CIBA-GEIGY CORPORATION (US) | 1997-04-29 | — | — | US | disclosed |
| US-5312914-A | Process for the manufacture of 4-acetoxy-3-hydroxyethyl-azetidinone | CIBA-GEIGY CORP (US) | 1994-05-17 | — | — | US | disclosed |
| US-5215997-A | Synthesis of beta-lactam compounds | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| US-5153315-A | Penicilllin deriviatives | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4962196-A | (3S, 4R)-3,4-trans-disubstituted azetidin-2-one intermediates | CIBA-GEIGY CORPORATION (US) | 1990-10-09 | — | — | US | disclosed |