Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129442 | 0.84 | MAPT (0.36) | ALDH1A1MAPTCASP1HSD17B10 | |
| SCHEMBL29401151 | 0.81 | ALDH1A1 (0.47) | ALDH1A1GAANPC1MAPTRAB9A | |
| SCHEMBL9646195 | 0.75 | MAPT (0.33) | MAPT | |
| SCHEMBL8918349 | 0.74 | ALDH1A1 (0.46) | ALDH1A1GAANPC1MAPTRAB9A | |
| SCHEMBL2028036 | 0.71 | LMNA (0.44) | ALDH1A1GAANPC1THRBATM | |
| Malonic Acid SCHEMBL11176995 | 0.69 | ALDH1A1 (0.60) | ALDH1A1NPC1MAPTRAB9ATHRB | |
| Bicarbonate SCHEMBL8397677 | 0.68 | ALDH1A1 (0.58) | ALDH1A1GAANPC1MAPTRAB9A | |
| SCHEMBL20858637 | 0.67 | ALDH1A1 (0.61) | ALDH1A1GAANPC1MAPTRAB9A | |
| SCHEMBL9487720 | 0.67 | ALDH1A1 (0.61) | ALDH1A1GAANPC1MAPTRAB9A | |
| SCHEMBL27814238 | 0.66 | ABCC4 (0.62) | ALDH1A1GAAMAPTLMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625059-A | Process for the manufacture of 4-acetoxy-3-hydroxyethyl-azetidinone | CIBA-GEIGY CORPORATION (US) | 1997-04-29 | — | — | US | disclosed |
| US-5312914-A | Process for the manufacture of 4-acetoxy-3-hydroxyethyl-azetidinone | CIBA-GEIGY CORP (US) | 1994-05-17 | — | — | US | disclosed |
| US-5215997-A | Synthesis of beta-lactam compounds | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| US-5153315-A | Penicilllin deriviatives | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4962196-A | (3S, 4R)-3,4-trans-disubstituted azetidin-2-one intermediates | CIBA-GEIGY CORPORATION (US) | 1990-10-09 | — | — | US | disclosed |