Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNB4 | O00305 | 1/20 | 0.54 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.54 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.54 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.54 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.54 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.54 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.54 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.54 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.54 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.54 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.54 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.54 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.54 |
| ▸ | CACNA2D4 | Q7Z3S7 | 1/20 | 0.54 |
| ▸ | CACNA2D3 | Q8IZS8 | 1/20 | 0.54 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137173 | 0.90 | AR (0.57) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL8975128 | 0.86 | HTT (0.48) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL8917192 | 0.86 | ALDH1A1 (0.65) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL10378083 | 0.86 | ALDH1A1 (0.74) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL8918577 | 0.85 | ALDH1A1 (0.72) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL8918613 | 0.84 | GAA (0.68) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL6137255 | 0.78 | SMN1; SMN2 (0.56) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL8918356 | 0.78 | ALDH1A1 (0.55) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL10378168 | 0.77 | ALDH1A1 (0.74) | ARALDH1A1MAPTPRKCZKDM4E | |
| SCHEMBL10379251 | 0.77 | AR (0.48) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670525-A | Substituted 4-phenyl-6-amino-nicotinic acid compounds useful in the treatment of CNS disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | claimed |
| EP-0705820-A1 | 6-Amino-nicotinic acid derivatives and their use as selective K-channel modulators | BAYER AG (DE) | 1996-04-10 | — | — | EP | claimed |
| US-5670525-A | Substituted 4-phenyl-6-amino-nicotinic acid compounds useful in the treatment of CNS disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0705820-A1 | 6-Amino-nicotinic acid derivatives and their use as selective K-channel modulators | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |