SCHEMBL8918389

SCHEMBL8918389

COc1ccccc1NC(=O)c1cccc(O)c1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.67
MEN1 O00255 5/20 0.64
METAP2 P50579 1/20 0.63
TUBB4A P04350 1/20 0.62
TUBB P07437 1/20 0.62
TUBA3C P0DPH7 1/20 0.62
TUBA1B P68363 1/20 0.62
TUBA4A P68366 1/20 0.62
TUBB4B P68371 1/20 0.62
TUBB3 Q13509 1/20 0.62
TUBB2A Q13885 1/20 0.62
TUBB8 Q3ZCM7 1/20 0.62
TUBA3E Q6PEY2 1/20 0.62
TUBA1A Q71U36 1/20 0.62
TUBA1C Q9BQE3 1/20 0.62
TUBB6 Q9BUF5 1/20 0.62
TUBB2B Q9BVA1 1/20 0.62
TUBB1 Q9H4B7 1/20 0.62
RAB9A P51151 3/20 0.62
TSHR P16473 3/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12368166 0.91 KMT2A (0.70) KMT2AMEN1METAP2TUBB4ATUBB
SCHEMBL12368159 0.89 KMT2A (0.77) KMT2AMEN1METAP2TUBB4ATUBB
SCHEMBL12368122 0.84 KMT2A (0.79) KMT2AMEN1METAP2RAB9ATSHR
SCHEMBL22851940 0.84 LMNA (0.67) KMT2AMEN1METAP2RAB9ATSHR
SCHEMBL12368164 0.83 KMT2A (0.64) KMT2AMEN1METAP2RAB9ATSHR
SCHEMBL12368197 0.83 KCNMA1 (0.74) KMT2AMEN1METAP2RAB9ATSHR
SCHEMBL926677 0.82 NPC1 (0.76) KMT2AMEN1METAP2RAB9ATSHR
SCHEMBL10890993 0.82 KMT2A (0.80) KMT2AMEN1METAP2TUBB4ATUBB
SCHEMBL7162767 0.81 CRHBP (0.73) KMT2AMEN1METAP2RAB9ATSHR
SCHEMBL14561928 0.81 KMT2A (0.58) KMT2AMEN1METAP2TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9118074-A None JP disclosed
JP-H09118074-A THERMAL RECORDING MATERIAL NIPPON KAYAKU CO LTD 1997-05-06 JP disclosed