SCHEMBL8918461

SCHEMBL8918461

CCOC(=O)C(OC)(O[C]=O)OCC

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 2/20 0.32
CYP4F2 P78329 3/20 0.32
CYP4A11 Q02928 3/20 0.32
THRB P10828 1/20 0.32
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HTT P42858 1/20 0.31
ALOX15 P16050 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30
SOAT1 P35610 1/20 0.30
PIN1 Q13526 1/20 0.30
MMP8 P22894 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8919014 0.91 PKM (0.39) PKMKDM4EMEN1KMT2AALDH1A1
SCHEMBL27861330 0.78 ALDH1A1 (0.46) PKMKDM4EMEN1KMT2AALDH1A1
SCHEMBL788715 0.78 ALDH1A1 (0.46) PKMKDM4EMEN1KMT2AALDH1A1
SCHEMBL5936809 0.76 ALDH1A1 (0.43) PKMKDM4EMEN1KMT2AALDH1A1
SCHEMBL7064864 0.71 CYP4F2 (0.43) PKMKDM4EMEN1KMT2AALDH1A1
SCHEMBL22863849 0.70 DGAT1 (0.33) PKMKDM4EALDH1A1THRBLMNA
SCHEMBL8919234 0.70 DGAT1 (0.33)
SCHEMBL8919594 0.69 MEN1 (0.34) PKMKDM4EMEN1KMT2AALDH1A1
SCHEMBL8919694 0.69 MEN1 (0.34) PKMKDM4EMEN1KMT2AALDH1A1
SCHEMBL2162997 0.68 ALDH1A1 (0.32) ALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5620944-A PRE- AND POST-EMERGENT WEED CONTROL NIHON NOHYAKU CO., LTD. (JP) 1997-04-15 US disclosed
EP-0590834-B1 Phenylimidazole derivatives, processes for production thereof, herbicides comprising said derivatives, and usages of said herbicides NIHON NOHYAKU CO LTD (JP) 1996-12-11 EP disclosed
EP-0590834-A1 Phenylimidazole derivatives, processes for production thereof, herbicides comprising said derivatives, and usages of said herbicides NIHON NOHYAKU CO., LTD. (JP) 1994-04-06 EP disclosed