Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846685 | 0.93 | PTGS2 (0.51) | PTGS2PTGS1PPARDALOX5 | |
| SCHEMBL7833513 | 0.88 | PTGS2 (0.53) | PTGS2PTGS1PPARDKMT2ANPC1 | |
| SCHEMBL7843634 | 0.87 | PTGS2 (0.55) | PTGS2PTGS1PPARDKMT2ARAB9A | |
| SCHEMBL6246548 | 0.87 | PTGS2 (0.65) | PTGS2PTGS1PPARDALOX5 | |
| SCHEMBL8918631 | 0.85 | PTGS2 (0.62) | PTGS2PTGS1PPARD | |
| SCHEMBL7841302 | 0.85 | PTGS2 (0.51) | PTGS2PTGS1PPARDKMT2ANPC1 | |
| SCHEMBL7843072 | 0.84 | PTGS2 (0.52) | PTGS2PTGS1PPARDALOX5 | |
| SCHEMBL7844271 | 0.84 | PTGS2 (0.53) | PTGS2PTGS1PPARDKMT2ANPC1 | |
| SCHEMBL7846132 | 0.82 | PTGS2 (0.53) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7833526 | 0.82 | PTGS2 (0.48) | PTGS2PTGS1PPARDALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668161-A | Substituted thiazoles for the treatment of inflammation | G.D. SEARLE & CO. (US) | 1997-09-16 | — | — | US | claimed |