Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917817 | 0.86 | PTGS2 (0.38) | PTGS2PTGS1 | |
| SCHEMBL8918665 | 0.85 | PTGS2 (0.39) | PTGS2PTGS1 | |
| SCHEMBL8917393 | 0.82 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL8921405 | 0.80 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL8918829 | 0.79 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL9233583 | 0.78 | PTGS2 (0.52) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL8920821 | 0.78 | PTGS2 (0.38) | PTGS2PTGS1 | |
| SCHEMBL8916673 | 0.77 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL8917890 | 0.77 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL8917301 | 0.76 | PTGS2 (0.45) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |