Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 3/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27574205 | 0.94 | NAAA (0.43) | ADH1ANAAAEPHX1THRATHRB | |
| SCHEMBL8918667 | 0.90 | ADH1A (0.44) | LMNAL3MBTL1HSD11B1ADH1APYGL | |
| SCHEMBL28004819 | 0.84 | EPHX1 (0.49) | ALDH1A1EPHX1EPHX2 | |
| SCHEMBL968899 | 0.82 | L3MBTL1 (0.46) | ALDH1A1LMNAL3MBTL1HSD11B1ADH1A | |
| SCHEMBL19570761 | 0.81 | L3MBTL1 (0.40) | LMNAL3MBTL1HSD11B1ADH1APYGL | |
| SCHEMBL5510945 | 0.81 | L3MBTL1 (0.42) | L3MBTL1HSD11B1ADH1APYGLNAAA | |
| SCHEMBL628951 | 0.81 | L3MBTL1 (0.42) | ALDH1A1LMNAPTBP1L3MBTL1HSD11B1 | |
| SCHEMBL970246 | 0.80 | L3MBTL1 (0.44) | ALDH1A1LMNAL3MBTL1HSD11B1ADH1A | |
| SCHEMBL9351634 | 0.80 | EPHX1 (0.51) | ALDH1A1EPHX1EPHX2 | |
| SCHEMBL18258653 | 0.80 | NAAA (0.45) | NAAAEPHX1THRATHRBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591762-A | HYPOTENSIVE AGENTS | DR. KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5459147-A | Angeotensin-antagonistic effects; hypotensive, antiischemic, and antidiabetic agents, treating glaucoma | DR. KARL THOMAE GMBH (DE) | 1995-10-17 | — | — | US | disclosed |