Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 7/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD5 | P21918 | 2/20 | 0.37 |
| ▸ | HTR1D | P28221 | 2/20 | 0.37 |
| ▸ | HTR1B | P28222 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916891 | 0.88 | DRD2 (0.38) | DRD2SLC6A4HTR2ADRD3ADRA2A | |
| Hydrochloric Acid SCHEMBL8916112 | 0.87 | DRD2 (0.37) | DRD2SLC6A4HTR2ADRD3ADRA2A | |
| SCHEMBL8916475 | 0.83 | DRD2 (0.40) | DRD2SLC6A4HTR2ADRD3ADRA2A | |
| SCHEMBL8916650 | 0.80 | DRD2 (0.39) | DRD2SLC6A4HTR2ADRD3ADRA2A | |
| SCHEMBL8917974 | 0.79 | DRD2 (0.38) | DRD2SLC6A4HTR2ADRD3ADRA2A | |
| SCHEMBL8917007 | 0.79 | CTSS (0.46) | DRD2SLC6A4HTR2ADRD3HTR7 | |
| Hydrochloric Acid SCHEMBL8916924 | 0.78 | CTSS (0.45) | DRD2SLC6A4HTR2ADRD3HTR7 | |
| SCHEMBL8916164 | 0.77 | CTSS (0.48) | DRD2SLC6A4HTR2ADRD3HTR7 | |
| Hydrochloric Acid SCHEMBL8918060 | 0.77 | CTSS (0.48) | DRD2SLC6A4HTR2ADRD3HTR7 | |
| Hydrochloric Acid SCHEMBL8920342 | 0.77 | CTSS (0.49) | DRD2SLC6A4HTR2ADRD3HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |