Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.37 |
| ▸ | THRA | P10827 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921504 | 1.00 | PDK2 (0.40) | PDK2PTPN11THRATHRBLTA4H | |
| SCHEMBL8922200 | 0.92 | PDK2 (0.35) | PDK2PTPN11THRATHRBLTA4H | |
| SCHEMBL8920247 | 0.92 | PDK2 (0.35) | PDK2PTPN11THRATHRBLTA4H | |
| SCHEMBL8920555 | 0.88 | PDK2 (0.34) | PDK2OPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL8920391 | 0.79 | CYP3A4 (0.36) | PDK2MEN1ALDH1A1GAAMAPT | |
| SCHEMBL8918856 | 0.78 | PDK2 (0.44) | PDK2PTPN11THRATHRBLTA4H | |
| SCHEMBL8920310 | 0.78 | PDK2 (0.44) | PDK2PTPN11THRATHRBLTA4H | |
| SCHEMBL8920255 | 0.78 | PDE5A (0.33) | PTPN11OPRK1MEN1MAPTKMT2A | |
| SCHEMBL8921238 | 0.77 | PRKCA (0.38) | OPRK1MEN1MAPTKMT2A | |
| SCHEMBL7824752 | 0.75 | PDK2 (0.47) | PDK2PTPN11THRATHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691272-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5559247-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0679640-A1 | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-11-02 | — | — | EP | disclosed |