Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.82 |
| ▸ | PGR | P06401 | 6/20 | 0.82 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.82 |
| ▸ | LMNA | P02545 | 2/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.82 |
| ▸ | USP2 | O75604 | 1/20 | 0.82 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.82 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.82 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.68 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | IL6 | P05231 | 1/20 | 0.53 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.53 |
| ▸ | GLUL | P15104 | 1/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595121 | 0.93 | NR3C1 (0.80) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL6858652 | 0.92 | NR3C1 (0.70) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL6858654 | 0.92 | NR3C1 (0.70) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL8918197 | 0.92 | NR3C1 (0.69) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL7598868 | 0.92 | NR3C1 (0.82) | NR3C1PGRHIF1ALMNACYP3A4 | |
| Prednicarbate SCHEMBL3941 | 0.91 | NR3C1 (1.00) | NR3C1PGRHIF1ALMNACYP3A4 | |
| Prednicarbate SCHEMBL1650745 | 0.91 | NR3C1 (1.00) | NR3C1PGRHIF1ALMNACYP3A4 | |
| Prednicarbate SCHEMBL3942 | 0.91 | NR3C1 (1.00) | NR3C1PGRHIF1ALMNACYP3A4 | |
| Prednicarbate SCHEMBL5483489 | 0.91 | NR3C1 (1.00) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL7594065 | 0.90 | NR3C1 (0.80) | NR3C1PGRHIF1ALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608093-A | ANTIINFLAMMATORY AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |
| EP-0666749-A1 | ENANTIOMERICALLY PURE beta-D-DIOXOLANE NUCLEOSIDES WITH SELECTIVE ANTI-HEPATITIS B VIRUS ACTIVITY | EMORY UNIVERSITY (US) | 1995-08-16 | — | — | EP | disclosed |
| EP-0640616-A2 | 17-Alkylcarbonate, 21-0-carbonic/carboxylic acid esters of corticosteroids, a method for their production and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-01 | — | — | EP | disclosed |
| WO-1994009793-A1 | ENANTIOMERICALLY PURE β-D-DIOXOLANE NUCLEOSIDES WITH SELECTIVE ANTI-HEPATITIS B VIRUS ACTIVITY | EMORY UNIVERSITY (US) | 1994-05-11 | — | — | WO | disclosed |